Author:
Saghafi Fatemeh,Mirzaie Farzaneh,Gorji Elham,Nabimeybodi Razieh,Fattahi Mehdi,Mahmoodian Hamed,Zareshahi Rahele
Abstract
Abstract
Background
Oils in traditional medicine are important products and used routinely for therapeutic purposes. Rose oil (Rosa damascene Mill), a product of Persian medicine, is advised for the treatment of Infectious diseases related to the female genitourinary tract. In the present study, R. damascena petal oil, aqueous, and hydroalcoholic extracts were evaluated for their in vitro antibacterial and anti-Trichomonas vaginalis effects.
Methods
Anti-trichomonas activity evaluation of extracts and oil were assayed by the Homocytometery method. Their antibacterial effects against Escherichia coli, methicillin-resistant Staphylococcus aureus, Pseudomonas aeruginosa, and clinically isolated Group B Streptococcus were assayed by broth microdilution in 96-well plates.
Results
The MIC of hydroalcoholic and aqueous extracts ranged from 25-50 and 25-100 mg/ml, respectively. Rose oil at all administered doses failed to show any antibacterial activity.
Conclusion
All extracts and oil concentrations showed some degree of growth inhibition activity on T. vaginalis; however, hydroalcoholic extract was more efficient.
Publisher
Springer Science and Business Media LLC
Subject
Complementary and alternative medicine
Reference50 articles.
1. Perumal S, Pillai S, Cai LW, et al. Determination of minimum inhibitory concentration of euphorbia hirta (L.) extracts by tetrazolium microplate assay. J Nat Prod. 2012;5(2):68–76.
2. Donadu MG, Trong Le N, Viet Ho D, et al. Phytochemical compositions and biological activities of essential oils from the leaves, rhizomes and whole plant of hornstedtia Bella Škorničk. Antibiotics. 2020;9(6). https://doi.org/10.3390/antibiotics9060334.
3. Gajdács M, Spengler G, Urbán E. Identification and antimicrobial susceptibility testing of anaerobic bacteria: Rubik’s cube of clinical microbiology? Antibiotics. 2017;6(4). https://doi.org/10.3390/antibiotics6040025.
4. Amanpour R, Abbasi-Maleki S, Neyriz-Naghadehi M, et al. Antibacterial effects of solanum tuberosum peel ethanol extract in vitro. J Herb Med Pharmacol. 2015;4(2):45–8.
5. Gajdács M. The concept of an ideal antibiotic: implications for drug design. Molecules. 2019;24(5):892. https://doi.org/10.3390/molecules24050892.
Cited by
10 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献