XELIRI-bevacizumab versus FOLFIRI-bevacizumab as first-line treatment in patients with metastatic colorectal cancer: a Hellenic Cooperative Oncology Group phase III trial with collateral biomarker analysis

Author:

Pectasides Dimitrios,Papaxoinis George,Kalogeras Konstantine T,Eleftheraki Anastasia G,Xanthakis Ioannis,Makatsoris Thomas,Samantas Epaminondas,Varthalitis Ioannis,Papakostas Pavlos,Nikitas Nikitas,Papandreou Christos N,Pentheroudakis George,Timotheadou Eleni,Koutras Angelos,Sgouros Joseph,Bafaloukos Dimitrios,Klouvas George,Economopoulos Theofanis,Syrigos Konstantinos N,Fountzilas George

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Oncology

Reference27 articles.

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2. Fuchs CS, Marshall J, Mitchell E, Wierzbicki R, Ganju V, Jeffery M, Schulz J, Richards D, Soufi-Mahjoubi R, Wang B, Barrueco J: Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: results from the BICC-C Study. J Clin Oncol. 2007, 25: 4779-4786. 10.1200/JCO.2007.11.3357.

3. Pritchard CC, Grady WM: Colorectal cancer molecular biology moves into clinical practice. Gut. 2011, 60: 116-129. 10.1136/gut.2009.206250.

4. Köhne CH, De Greve J, Hartmann JT Lang I, Vergauwe P, Becker K, Braumann D, Joosens E, Müller L, Janssens J, Bokemeyer C, Reimer P, Link H, Späth-Schwalbe E, Wilke HJ, Bleiberg H, Van Den Brande J, Debois M, Bethe U, Van Cutsem E: Irinotecan combined with infusional 5-fluorouracil/folinic acid or capecitabine plus celecoxib or placebo in the first-line treatment of patients with metastatic colorectal cancer. EORTC study 40015. Ann Oncol. 2008, 19: 920-926. 10.1093/annonc/mdm544.

5. García-Alfonso P, Muñoz-Martin AJ, Alvarez-Suarez S, Jerez-Gilarranz Y, Riesco-Martinez M, Khosravi P, Martin M: Bevacizumab in combination with biweekly capecitabine and irinotecan, as first-line treatment for patients with metastatic colorectal cancer. Br J Cancer. 2010, 103: 1524-1528. 10.1038/sj.bjc.6605907.

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