Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase-Reference-Cited by-同舟云学术

Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase

Published:2010-12 Issue:1 Volume:10 Page:
ISSN:1471-2407
Container-title:BMC Cancer
language:en
Short-container-title:BMC Cancer

Author:

Olesen Uffe H,Petersen Jakob G,Garten Antje,Kiess Wieland,Yoshino Jun,Imai Shin-Ichiro,Christensen Mette K,Fristrup Peter,Thougaard Annemette V,Björkling Fredrik,Jensen Peter B,Nielsen Søren J,Sehested Maxwell

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Oncology

Link

http://link.springer.com/content/pdf/10.1186/1471-2407-10-677.pdf

Reference45 articles.

1. Janne PA, Gray N, Settleman J: Factors underlying sensitivity of cancers to small-molecule kinase inhibitors. Nat Rev Drug Discov. 2009, 8 (9): 709-723. 10.1038/nrd2871.

2. Gorre ME, Mohammed M, Ellwood K, Hsu N, Paquette R, Rao PN, Sawyers CL: Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science. 2001, 293 (5531): 876-880. 10.1126/science.1062538.

3. Gorre ME, Sawyers CL: Molecular mechanisms of resistance to STI571 in chronic myeloid leukemia. Curr Opin Hematol. 2002, 9 (4): 303-307. 10.1097/00062752-200207000-00007.

4. O'Hare T, Corbin AS, Druker BJ: Targeted CML therapy: controlling drug resistance, seeking cure. Curr Opin Genet Dev. 2006, 16 (1): 92-99. 10.1016/j.gde.2005.11.002.

5. Ziegler M: New functions of a long-known molecule. Emerging roles of NAD in cellular signaling. Eur J Biochem. 2000, 267 (6): 1550-1564. 10.1046/j.1432-1327.2000.01187.x.

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