Phase 1-2a multicenter dose-escalation study of ezatiostat hydrochloride liposomes for injection (Telintra®, TLK199), a novel glutathione analog prodrug in patients with myelodysplastic syndrome

Author:

Raza Azra,Galili Naomi,Callander Natalie,Ochoa Leonel,Piro Lawrence,Emanuel Peter,Williams Stephanie,Burris Howard,Faderl Stefan,Estrov Zeev,Curtin Peter,Larson Richard A,Keck James G,Jones Marsha,Meng Lisa,Brown Gail L

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,Molecular Biology,Hematology

Reference13 articles.

1. Kouides PA, Bennett JM: Morphology and classification of myelodysplastic syndromes. Hematol Oncol Clin North Am. 1992, 6: 485-499.

2. Weisdorf DJ, Oken MM, Johnson GJ, Rydell RE: Chronic myelodysplastic syndrome: Short survival with or without evolution to acute leukaemia. Br J Haematol. 1983, 55: 691-700. 10.1111/j.1365-2141.1983.tb02852.x.

3. Mufti GJ, Galton DAG: Myelodysplastic Syndromes: Natural History and Features of Prognostic Importance. Clinics in Haematology. Edited by: Griffin JD. 1986, London, UK: W.B. Saunders Company, 953-971.

4. Bennett JM: Classification of the Myelodysplastic Syndromes. Clinics in Haematology. Edited by: Griffin JD. 1986, London, UK: W. B. Saunders Company, 909-923.

5. Morgan AS, Stanboli A, Sanderson PE: TER199 Increases Bone Marrow (BM) CFU-GM and Peripheral Platelet and Neutrophil Counts in Myelosuppressed Rodents. Proceedings of the Annual Meeting of the American Society of Hematology; December 6–10. 1996, 134b- ; Orlando, Florida. Abstract #3263

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