Spatially resolved transcriptomics in immersive environments

Author:

Bienroth Denis,Nim Hieu T.,Garkov Dimitar,Klein KarstenORCID,Jaeger-Honz Sabrina,Ramialison Mirana,Schreiber Falk

Abstract

AbstractSpatially resolved transcriptomics is an emerging class of high-throughput technologies that enable biologists to systematically investigate the expression of genes along with spatial information. Upon data acquisition, one major hurdle is the subsequent interpretation and visualization of the datasets acquired. To address this challenge, VR-Cardiomicsis presented, which is a novel data visualization system with interactive functionalities designed to help biologists interpret spatially resolved transcriptomic datasets. By implementing the system in two separate immersive environments, fish tank virtual reality (FTVR) and head-mounted display virtual reality (HMD-VR), biologists can interact with the data in novel ways not previously possible, such as visually exploring the gene expression patterns of an organ, and comparing genes based on their 3D expression profiles. Further, a biologist-driven use-case is presented, in which immersive environments facilitate biologists to explore and compare the heart expression profiles of different genes.

Funder

Deutsche Forschungsgemeinschaft

ARC Discovery Project

NH & MRC

Publisher

Springer Science and Business Media LLC

Subject

Computer Graphics and Computer-Aided Design,Computer Vision and Pattern Recognition,Visual Arts and Performing Arts,Medicine (miscellaneous),Computer Science (miscellaneous),Software

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Beyond the horizon: immersive developments for animal ecology research;Visual Computing for Industry, Biomedicine, and Art;2023-06-20

2. Immersive analytics: An overview;it - Information Technology;2022-08-01

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