Author:
Huang Haidong,Li Chen,Bai Chong,Li Qiang,Zheng Weiqiang,Zhu Zhi,Zarogoulidis Paul,Zarogoulidis Konstantinos,Gschwendtner Andreas,Hohenforst-Schmidt Wolfgang,Simoff Michael
Abstract
Abstract
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We present a case of 39-year-old male with the symptoms of fever, cough, chest pain and bloody phlegm, whose chest CT showed multiple subpleural nodules and inflammatory infiltration. Video-Assisted Thoracic Surgery ( VATS ) for right subplural nodule was performed and confirmed the diagnosis of necrotizing sarcoid granulomatosis. Prednisolone was administered and the symptoms were under control untill the occurrence of intermittent hemoptysis after 10 months. Chest CT and bronchoscope revealed the right lower lobe nodule with intraluminal necrotic tissue in the right lower lobe posterior basal segment respectively. Fatal hemoptysis happened during endobronchial biopsy by flexible bronchoscope forcep. Based on this case, we reviewed the relevant literature and discussed the clinical features, pathological changes and prognosis of the disease.
Publisher
Springer Science and Business Media LLC
Subject
General Medicine,Histology,Pathology and Forensic Medicine
Reference30 articles.
1. Liebow AA: The J. Burns Amberson lecture–pulmonary angiitis and granulomatosis. Am Rev Respir Dis. 1973, 108 (1): 1-18.
2. Koss MN, Hochholzer L, Feigin DS, Garancis JC, Ward PA: Necrotizing sarcoid-like granulomatosis: clinical, pathologic, and immunopathologic findings. Hum Pathol. 1980, 11 (5 Suppl): 510-519.
3. Tauber E, Wojnarowski C, Horcher E, Dekan G, Frischer T: Necrotizing sarcoid granulomatosis in a 14-yr-old female. Eur Respir J. 1999, 13 (3): 703-705. 10.1183/09031936.99.13370399.
4. Analytical Lung Pathology. Edited by: Kayser K. 1992, Heidelberg: Springer
5. Heinrich D, Gordjani N, Trusen A, Marx A, Hebestreit H: Necrotizing sarcoid granulomatosis: a rarity in childhood. Pediatr Pulmonol. 2003, 35 (5): 407-411. 10.1002/ppul.10242.
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