Author:
Kao Yu-Chien,Chow Jyh-Ming,Wang Kum-Min,Fang Chia-Lang,Chu Jan-Show,Chen Chi-Long
Abstract
Abstract
Primary pleural angiosarcoma is a rare and clinically aggressive tumor. Patients usually present with chest pain, dyspnea, hemoptysis and/or cough. Radiologic studies reveal diffuse pleural thickening and pleural effusion with or without mass lesion. The clinical and radiological features both resemble those of mesothelioma, and its definite diagnosis requires careful histologic examination. However, frequent epithelioid feature and immunoreactivity to cytokeratin in primary pleural angiosarcoma further complicate the pathologic diagnosis. The use of proper immunohistochemical stains is often needed to support endothelial differentiation in the tumor cells and to exclude metastatic carcinoma and mesothelioma. We report the case of a 49-year-old male patient with primary pleural angiosarcoma, who presented with initial hemothorax, followed by a rapid progress to an inoperable status.
Virtual Slides
The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1059343251633446
Publisher
Springer Science and Business Media LLC
Subject
General Medicine,Histology,Pathology and Forensic Medicine
Reference25 articles.
1. Dainese E, Pozzi B, Milani M, Rossi G, Pezzotta MG, Vertemati G, Tricomi P, Sessa F: Primary pleural epithelioid angiosarcoma. A case report and review of the literature. Pathol Res Pract. 2010, 206 (6): 415-419. 10.1016/j.prp.2009.11.008.
2. Stout AP: Hemangio-Endothelioma: A Tumor of Blood Vessels Featuring Vascular Endothelial Cells. Ann Surg. 1943, 118 (3): 445-464.
3. Ximenes M, Miziara HL: Hemangioendothelioma of the lung and pleura: report of three cases. Int Surg. 1981, 66 (1): 67-70.
4. McCaughey WT, Dardick I, Barr JR: Angiosarcoma of serous membranes. Arch Pathol Lab Med. 1983, 107 (6): 304-307.
5. Aozasa K, Naka N, Tomita Y, Ohsawa M, Kanno H, Uchida A, Ono K: Angiosarcoma developing from chronic pyothorax. Mod Pathol. 1994, 7 (9): 906-911.
Cited by
21 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献