Novel long noncoding RNA OTUD6B-AS1 indicates poor prognosis and inhibits clear cell renal cell carcinoma proliferation via the Wnt/β-catenin signaling pathway

Author:

Wang Gang,Zhang Zi-jian,Jian Wen-gang,Liu Pan-hong,Xue Wei,Wang Teng-da,Meng Yu-yang,Yuan Chao,Li Hao-ming,Yu Yi-peng,Liu Zhan-xin,Wu Qiong,Zhang Da-ming,Zhang Cheng

Funder

National Natural Science Foundation of China

The First Affiliated Hospital of Harbin Medical University Science Foundation

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,Molecular Medicine

Reference40 articles.

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2. Espanaagusti J, Warren A, Su KC, et al. Loss of PBRM1 rescues VHL dependent replication stress to promote renal carcinogenesis. Nat Commun. 2017;8(1):2026.

3. Tan X, Liu Y, Hou J, et al. Targeted therapies for renal cell carcinoma in Chinese patients: focus on everolimus. Onco Targets Ther. 2015;8(default):313–21.

4. Wei Z. AB106. Differential regulation of LncRNA-SARCC suppresses VHL-mutant RCC cell proliferation yet promotes VHL-normal RCC cell proliferation via modulating androgen receptor/HIF-2α/C-MYC axis under hypoxia. Oncogene. 2016;5(Suppl 1):4866–80.

5. Fan Y, Li H, Ma X, et al. Dicer suppresses the malignant phenotype in VHL-deficient clear cell renal cell carcinoma by inhibiting HIF-2α. Oncotarget. 2016;7(14):18280–94.

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