The role of m6A methylation in therapy resistance in cancer-Reference-Cited by-同舟云学术

The role of m6A methylation in therapy resistance in cancer

Published:2023-06-01 Issue:1 Volume:22 Page:
ISSN:1476-4598
Container-title:Molecular Cancer
language:en
Short-container-title:Mol Cancer

Author:

Zhuang Hengzhao,Yu Bo,Tao Dan,Xu Xiaoyan,Xu Yijun,Wang Jian,Jiao Yang,Wang Lili

Abstract

AbstractCancer therapy resistance is the main cause of cancer treatment failure. The mechanism of therapy resistance is a hot topic in epigenetics. As one of the most common RNA modifications, N6-methyladenosine (m6A) is involved in various processes of RNA metabolism, such as stability, splicing, transcription, translation, and degradation. A large number of studies have shown that m6A RNA methylation regulates the proliferation and invasion of cancer cells, but the role of m6A in cancer therapy resistance is unclear. In this review, we summarized the research progress related to the role of m6A in regulating therapy resistance in cancers.

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,Molecular Medicine

Link

https://link.springer.com/content/pdf/10.1186/s12943-023-01782-2.pdf

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