Author:
Liu Fuyao,Lin Danting,Zheng Ce,Wang Geng
Abstract
Abstract
Background
To study the iridolenticular contact area (ILCA) under different light conditions in acute primary angle closure (APAC).
Methods
This cross-sectional, observational study involved 22 unilateral APAC patients and 59 cataract patients (59 eyes). Images of the APAC eyes, fellow eyes and cataract eyes were collected by anterior segment optical coherence tomography (ASOCT) under different light conditions respectively. The ILCA, anterior chamber width (ACW), anterior chamber area (ACA), lens vault (LV), angle opening distance at 750 μm (AOD750), trabecular iris space area at 750 μm (TISA750) and iris area at 750 μm (IA750) were measured using Image J software.
Results
The ILCA of cataract eyes were significantly larger than APAC eyes (4.424 ± 1.208 vs 4.049 ± 2.725mm2, P = 0.034) and fellow eyes (4.424 ± 1.208 vs 3.651 ± 1.629 mm2, P = 0.008) under dark condition. Under dark condition, ILCA of APAC eyes was negatively correlated with AOD750 (r = -0.444, P = 0.038), TISA750 (r = -0.498, P = 0.018). The ILCA of cataract eyes under dark condition was significantly greater than under bright condition (4.424 ± 1.208 vs 2.526 ± 0.992 mm2, P < 0.001).
Conclusions
This study showed that ILCA in both APAC eye and fellow eye were smaller than cataract eye. Future study should focus on both the contact area and force at the interface of lens and iris with larger sample size.
Funder
National Nature Science Foundation of China
Guangdong Medical Research Foundation
Shantou Municipal Science and Technology Project
2020 Li Ka Shing Foundation Cross-Disciplinary Research Grant
Publisher
Springer Science and Business Media LLC
Subject
Ophthalmology,General Medicine
Cited by
1 articles.
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