Abstract
AbstractBackgroundTo investigate the new cornea biomechanical parameter stress-strain index (SSI) in Chinese healthy people and the factors associated with SSI.MethodsA total of 175 eyes from 175 participants were included in this study. Axial length was measured with the Lenstar LS-900. Pentacam measured curvature of the cornea and anterior chamber volume (ACV). Cornea biomechanical properties assessments were performed by corneal visualization Scheimpflug technology (Corvis ST). Student’s t-test, one-way ANOVA, partial least square linear regression (PLSLR) and linear mixed effects (LME) model were used in the statistical analysis.ResultsThe mean (±SD) SSI was 1.14 ± 0.22 (range, 0.66–1.78) in all subjects and affected by age significantly after age of 35 (P < 0.05). In LME models, SSI was significantly associated with age (β = 0.526,P < 0.001), axial length (AL) (β = − 0.541,P < 0.001), intraocular pressure (IOP) (β = 0.326,P < 0.001) and steepest radius of anterior corneal curvature (RsF) (β = 0.229,P < 0.001) but not with ACV, biomechanical corrected intraocular pressure (bIOP), flattest radius of anterior corneal curvature (RfF) or central corneal thickness (CCT) (P > 0.05 for each).ConclusionsSSI increased with age after the age of 35. In addition to age, SSI was positively correlated with RsF and IOP, while negatively correlated with AL.
Funder
Natural Science Foundation of Tianjin City
Publisher
Springer Science and Business Media LLC
Subject
Ophthalmology,General Medicine
Cited by
21 articles.
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