Association between previous cataract surgery and cognition among middle-aged and older Chinese: the China health and retirement longitudinal study (CHARLS)
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Published:2023-05-31
Issue:1
Volume:23
Page:
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ISSN:1471-2415
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Container-title:BMC Ophthalmology
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language:en
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Short-container-title:BMC Ophthalmol
Author:
Zhao Xiaohuan,Wei Kunchen,Sun Junran,Chen Jieqiong,Wang Yimin,Chen Yuhong,Zhu Xinyue,Sun Xiaodong,Li Tong,Zhou Minwen
Abstract
Abstract
Background
Cataract is the primary cause of blindness globally, and surgery offers the only method by which to remove cataracts. We aimed to examine whether previous cataract surgery is associated with cognitive function.
Methods
Our study included 13,824 participants. Data from the baseline of the China Health and Retirement Longitudinal Study (CHARLS) were used. The participants were categorized into two groups: with and without previous cataract surgery. Weighted multiple linear regression was used to obtain the β and 95% confidence intervals (CI).
Results
The participants who had previous cataract surgery (n = 261) scored lower in cognition, including both memory and mental state, than those without previous cataract surgery. After adjusting for socioeconomic factors and metabolic measures, a negative association was evident between previous cataract surgery and cognition (β = −0.647, 95% CI: −1.244, − 0.049). Furthermore, the participants who were older and female demonstrated a decline in cognition, while living in cities and having higher levels education were associated with higher cognition.
Conclusions
Better cognitive function was associated with less previous cataract surgery or cataract occurrence. This suggests that a period of vision loss due to cataract leads to cognitive decline, however further studies are need to dissect the impact of vision loss and cataract surgery on cognitive decline.
Funder
National Natural Science Foundation of China
National Key R&D Program
Shanghai Hospital Development Center
Science and Technology Commission of Shanghai Municipality
Shanghai Natural Science Foundation
Shanghai Pujiang Program
Publisher
Springer Science and Business Media LLC
Subject
Ophthalmology,General Medicine