Abstract
Abstract
Background
Herein, we report two cases of unilateral retinal pigment epithelium dysgenesis (URPED) in Chinese patients and explore the relationship between URPED and combined hamartoma of the retina and retinal pigment epithelium (CHRRPE).
Case presentation
The lesion margins in the two cases showed pathognomonic clinical features of URPED, namely, a scalloped reticular margin in hyperplastic retinal pigment epithelium and mild fibrosis. The hypoautofluorescence observed by fundus autofluorescence was inverted compared with that observed by fundus fluorescence angiography. A large amount of fibroglial proliferation and disorganization of the retina involving the whole layer, which are also found in peripapillary CHRRPE, were found in the lesions.
Conclusions
URPED appears to share some clinical features with CHRRPE, and the relationship between URPED and CHRRPE needs further study.
Funder
department of finance of jilin province
Publisher
Springer Science and Business Media LLC
Subject
Ophthalmology,General Medicine
Reference14 articles.
1. Salomon Y. Cohen, Pascale Massin, Gabriel Quentel. Unilateral, idiopathic leopard-spot lesion of the retinal pigment epithelium. Arch Ophthalmol. 2002;120(4):512–6.
2. Cohen S, Fung A, Tadayoni R, et al. Unilateral Retinal Pigment Epithelium Dysgenesis. Am J Ophthalmol. 2009;148:914–9 e912.
3. Krohn J, Ommundsen K, Hanken G. Slowly progressive unilateral retinal pigment epithelium dysgenesis leading to severe visual impairment. Acta Ophthalmol. 2018;96(6):758–60.
4. Shimoyama T, Imai H, Honda S, Negi A. A case of choroidal neovascularization secondary to unilateral retinal pigment epithelium dysgenesis. Case Rep Ophthalmol. 2014;5:34–7.
5. Şekeryapan GB. A rare cause of type II neovascularization: unilateral retinal pigment epithelium dysgenesis. Turk J Ophthalmol. 2020;50(3):187–9.
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献