Two novel amino acid substitutions in highly conserved regions of prion protein (PrP) and a high frequency of a scrapie protective variant in native Ethiopian goats
Author:
Funder
Ministero della Salute
Publisher
Springer Science and Business Media LLC
Subject
General Veterinary,General Medicine
Link
http://link.springer.com/content/pdf/10.1186/s12917-019-1870-4.pdf
Reference43 articles.
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2. Lee JH, Bae SE, Jung S, Ahn I, Son HS. Discriminant analysis of prion sequences for prediction of susceptibility. Exp Mol Med. 2013;45(10):e48.
3. Lysek DA, Schorn C, Nivon LG, Esteve-Moya V, Christen B, Calzolai L, von Schroetter C, Fiorito F, Herrmann T, Guntert P, Wuthrich K. Prion protein NMR structures of cats, dogs, pigs, and sheep. Proc Natl Acad Sci U S A. 2005;102(3):640–5.
4. Collinge J, Clarke AR. A general model of prion strains and their pathogenicity. Science. 2007;318:930–6.
5. EFSA Biohaz Panel. Genetic resistance to transmissible spongiform encephalopathies (TSE) in goats. EFSA J. 2017;15(8):4962.
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