Abstract
Abstract
Background
In dogs, meningiomas mostly cause chronic progressive clinical signs due to slow tumor growth.
Case presentation
In contrast, three dogs were presented with the history of chronic generalized tonic-clonic seizures and peracute deterioration with sudden onset of neurological deficits in accordance with an extensive unilateral forebrain lesion. Magnetic resonance imaging examinations of the dogs revealed a well-delineated extraaxial T2W hyperintense mass in the rostral forebrain with homogeneous contrast enhancement. Additionally, an intraaxial, well-demarcated, unilateral lesion was apparent in the parenchyma supplied by the middle cerebral artery. In two cases, necropsy revealed meningothelial meningioma in the rostral fossa and marked eosinophilic neuronal necrosis, a sign of ischemia, focal malacia, edema and gliosis in the temporal lobe and hippocampus because of a focal thrombosis of the middle cerebral artery. In the third case symptomatic treatment resulted in improvement of clinical signs enabling a good quality of life for the patient.
Conclusions
In dogs with structural epilepsy caused by meningioma, acute deterioration of clinical signs can be associated with ischemic infarctions as a potential complication.
Publisher
Springer Science and Business Media LLC
Subject
General Veterinary,General Medicine
Reference26 articles.
1. Dewey CW, Da Costa RC, editors. Practical guide to canine and feline neurology. Hoboken: Wiley; 2015.
2. Snyder JM, Shofer FS, Van Winkle TJ, Massicotte C. Canine intracranial primary neoplasia: 173 cases (1986–2003). J Vet Intern Med. 2006;20(3):669–75.
3. Sessums K, Mariani C. Intracranial meningioma in dogs and cats: a comparative review. Compendium. 2009;31(7):330–9.
4. Motta L, Mandara MT, Skerritt GC. Canine and feline intracranial meningiomas: an updated review. Vet J. 2012;192(2):153–65.
5. Perry A, Brat DJ. Practical surgical neuropathology: a diagnostic approach. Amstredam: Elsevier Health Sciences; 2010.
Cited by
4 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献