Author:
Wan Shuangxiu,Sun Na,Li Hongquan,Khan Ajab,Zheng Xiaozhong,Sun Yaogui,Fan Ruiwen
Abstract
Abstract
Background
In the livestock feed industry, feed and feed raw materials are extremely susceptible to mycotoxin contamination. Deoxynivalenol (DON) is one of the main risk factors for mycotoxin contamination in broiler feed and feedstuff, however, there is still little knowledge about this. Hence, the purpose of this study was to explore the toxicity effect of DON on the intestinal barrier and the microecological balance of the biota in broiler chickens.
Results
In our present study, we compared the pathological scores of the small intestines of broilers on the 5th, 7th, and 10th day, and chose the 7th day to analyze the small intestine histomorphology, tight junctions, and cecal biota of the broilers. The results showed the damage to the small intestine worsened over time, the small intestinal villi of broilers were breakage, the tight junctions of the small intestine were destroyed, the cecal biota was unbalanced, and the growth performance of broilers was reduced on the 7th day.
Conclusions
DON could damage the functional and structural completeness of the intestinal tract, disorder the Intestinal biota, and finally lead to declined broiler performance. Our study provided a basis for the prevention and treatment of DON in broiler production.
Funder
Key Technologies Research and Development Program
Shanxi “1331 Project”
Publisher
Springer Science and Business Media LLC
Subject
General Veterinary,General Medicine
Cited by
5 articles.
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