Abstract
Abstract
Background
Carbofuran is a widely used broad-spectrum pesticide that, despite strict regulation and being banned for more than a decade, is still encountered in cases of intentional poisoning in dogs and wildlife. The objective of the study was to provide a complete and detailed description of the pathological, histological and toxicological findings of 7 cases of intentional carbofuran poisoning in dogs.
Results
In this retrospective study, 7 cases of carbofuran intoxication recorded from July 2015 to June 2017 were analyzed. Following complete history recording, all cases were examined by complete necropsy and histopathology. Carbofuran intoxication was confirmed in all cases by gas chromatography. The postmortem examination revealed extensive hemorrhaging and congestion located mainly within the respiratory, nervous and cardiovascular systems, accompanied by degeneration and necrosis within the lungs, heart, and kidneys.
Conclusions
Although carbamates have been banned in the European Union, carbamate poisoning is still frequently encountered, especially in wild animals. This paper will contribute to a better understanding of the occurrence and pathogenesis of acute carbofuran exposure in dogs and contribute some peculiar pathological features of this type of poisoning to the current literature.
Publisher
Springer Science and Business Media LLC
Subject
General Veterinary,General Medicine
Reference46 articles.
1. Plumlee KH. Clinical veterinary toxicology: Mosby; 2004. https://doi.org/10.1016/B0-323-01125-X/X5001-8.
2. World Health Organization. The WHO recommended classification of pesticides by hazard and guidelines to classification. Geneva; 2009.
3. Ngaio R: Carbofuran and wildlife poisoning. 2012. ePDF 978–1–119-99854-9; Wiley Online Library 978–1–119-99853-2; ePub 978–1–119-95110-0; Mobi 978–1–119-9511-7.
4. Baron RL. A carbamate insecticide: a case study of aldicarb. Environmental Health Perspective. 1994;102:23–7.
5. U.S. Environmental Protection Agency. (Oct. 18). Carbofuran: requests to amend registrations to delete certain uses and final determination with respect to those uses. Fed Regist. 1990;55(202):42266–8.
Cited by
4 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献