Author:
Bhagwat Ashlesha,Annapure Uday S.
Abstract
Abstract
Background
Cesarean delivery (c-section) is on the rise globally. C-section is generally preferred if complications prevail in a vaginal delivery. Some private institutions conduct it unnecessarily for economic gains. This has led to a severe risk to a child’s health. The neonate’s gut microbiota has been observed to be influenced by the mode of delivery. Lactobacilli and other bacteria are very vital for developing healthy gut flora. An attempt has been made to investigate the passage of lactic acid bacteria to the infant via delivery. The vaginal swabs of the mothers and fresh meconium samples of the newborns post-delivery were examined for the presence of lactobacilli through culture techniques.
Results
The present investigation revealed that c-section-delivered infants lacked these bacteria in comparison with vaginally delivered infants. Biochemical tests and 16S rRNA sequencing showed similarity with groups 1, 2, 3, and 5 of Enterococcus genus. Phylogenetic analysis revealed more than 98% similarity with several Enterococcus species. E. canintestini, E.rivorum, and E. dispar were transferred frequently from mother to infants born via vaginal delivery. The strains were submitted to the NCBI GenBank database under accession numbers KX830968–KX830982.
Conclusion
The study supports the hypothesis of maternal-neonatal transmission of bacteria during delivery and also possibilities of isolating newer strains for probiotic use.
Publisher
Springer Science and Business Media LLC
Reference45 articles.
1. Gibbons L, Belizán JM, Lauer JA (2010) The global numbers and costs of additionally needed and unnecessary caesarean sections performed per year: overuse as a barrier to universal coverage. World Heal Rep Backgr Pap:1–31
2. Osterman MJK, Martin JA (2014) National vital statistics reports primary cesarean delivery rates, by state: results from the revised birth certificate, 2006 – 2012, p 63
3. Nazneen R, Begum R, Sultana K (1970) Rising trend of caesarean section in a tertiary hospital over a decade. J Bangladesh Coll Physicians Surg. https://doi.org/10.3329/jbcps.v29i3.9432
4. A TR. Increasing trend of caesarean rates in India: evidence from NFHS-4. J Med Sci Clin Res 2017;5:26167–26176. doi: https://doi.org/10.18535/jmscr/v5i8.31.
5. Gosalbes MJ, Llop S, Moya A (2013) Meconium microbiota types dominated by lactic acid or enteric bacteria are differentially associated with maternal eczema and respiratory problems in infants. Clin Exp Allergy 43:198–211. https://doi.org/10.1111/cea.12063
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