Abstract
Abstract
Background
This study aimed to assess the clinical and hemato-biochemical changes associated with diarrhea in E. coli and Salmonella pathogens in Friesian bovine calves less than one month old as well as to examine the relationship between Vit D3 and cardiac biomarkers.
Results
The study was carried out on 43 Friesian calves from a private farm in Ash Sharqia Governorate, 33 diarrheic calves aged 1–14 days with an average body weight 43.7 ± 1.2 kg, and 10 apparently healthy calves were kept as a control group to investigate the clinical and hemato-biochemical profiles. E. coli and Salmonella pathogens were isolated from the diarrheic calves where 76% were E. coli and 24% were Salmonella. Diarrheic calves showed signs of anorexia, weakness, dullness, staggering gait, pale mucous membranes with sunken eyes and dehydration. Analysis of clinical and hemato-biochemical profile of the diarrheic calves revealed significant increase in body temperature, respiratory rate, heart rate, white blood cells, neutrophils, serum potassium, urea, creatinine, ALT, AST, cardiac NT-proBNP and cardiac troponin I with significant decrease in hemoglobin, packed cell volume, erythrocytes, serum Vit D3, sodium, glucose, total protein and albumin concentrations.
Conclusions
It could be concluded that bacterial diarrhea has a severe negative impact on the clinical and hemato-biochemical profile of the neonatal calves with diarrhea. Serum cardiac biomarkers such as cardiac troponin I (cTn-I) and NT-proBNP were significantly higher in neonatal calves with diarrhea, and there is an important relationship between cardiac biomarkers and vitamin D levels.
Publisher
Springer Science and Business Media LLC
Subject
Pharmaceutical Science,Agricultural and Biological Sciences (miscellaneous),Medicine (miscellaneous)
Reference46 articles.
1. Altuğ N, Yuksek N, Ozkan C, Keleş I, Başbuğan Y, Ağaoğlu ZT, Kaya A, Akgul Y (2013) Rapid etiological diagnosis of neonatal calf diarrhoea with immunochromatographic test kits. Van Vet J 24:123–128
2. Uetake K (2013) Newborn calf welfare: a review focusing on mortality rates. Anim Sci J Nihon chikusan Gakkaiho 84:101–105
3. Stoltenow CL, Vincent LL. Calf scours: causes, prevention, and treatment. North Dakota State University. Extension Service. 2003; AS-776 1-4.
4. Katsoulos PD, Karatzia MA, Dovas CI, Filioussis G, Papadopoulos E, Kiossis E, Arsenopoulos K, Papadopoulos T, Boscos C, Karatzias H (2017) Evaluation of the in-field efficacy of oregano essential oil administration on the control of neonatal diarrhea syndrome in calves. Res Vet Sci 115:478–483
5. Bartels CJ, Holzhauer M, Jorritsma R, Swart WA, Lam TJ (2010) Prevalence, prediction and risk factors of enteropathogens in normal and non-normal faeces of young Dutch dairy calves. Prev Vet Med 93:162–169