Author:
Peng Dacheng,Wang Huashan,Qu Chenling,Xie Laihua,Wicks Sheila M,Xie Jingtian
Abstract
Abstract
Ginsenosides, the bioactive components of ginseng, can be divided into two major groups, namely 20(S)-protopanaxatriol (e.g. Re, Rg1, Rg2, and Rb3) and 20(S)-protopanaxadiol (e.g. Rb1, Rb2, Rc, and Rd). Biological and environmental factors may affect the content of ginsenosides in different parts of ginseng plant. Evidence from pharmacokinetic and metabolic studies of Re demonstrated that (1) the absorption of Re is fast in gastrointestinal tract; (2) Re may be metabolized mainly to Rh1 and F1 by intestinal microflora before absorption into blood; and (3) Re is quickly cleared from the body.
Publisher
Springer Science and Business Media LLC
Subject
Complementary and alternative medicine,Pharmacology
Reference61 articles.
1. Lu JM, Yao Q, Chen C: Ginseng compounds: an update on their molecular mechanisms and medical applications. Curr Vasc Pharmacol. 2009, 7 (3): 293-302.
2. Peng DC, Chen WP, Xie JT: Antihyperglycemic effects of ginseng and possible mechanisms. Drugs of the future. 2008, 33 (6): 507-514.
3. Hofseth LJ, Wargovich MJ: Inflammation, cancer, and targets of ginseng. J Nutr. 2007, 137 (1 Suppl): 183S-185S.
4. Chevallier A: Encyclopedia of herbal medicine. 2000, New York: DK Publishing Inc
5. Blumenthal M, Goldberg A, Brinckmann J: Ginseng root. 2000, Newton, MA: Integrative Medicine Communications
Cited by
49 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献