Cytoplasmic location of factor-inhibiting hypoxia-inducible factor is associated with an enhanced hypoxic response and a shorter survival in invasive breast cancer

Author:

Tan Ern Yu,Campo Leticia,Han Cheng,Turley Helen,Pezzella Francesco,Gatter Kevin C,Harris Adrian L,Fox Stephen B

Publisher

Springer Science and Business Media LLC

Reference43 articles.

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2. Hohenberger P, Felgner C, Haensch W, Schlag PM: Tumor oxygenation correlates with molecular growth determinants in breast cancer. Breast Cancer Res Treat. 1998, 48: 97-106. 10.1023/A:1005921513083.

3. Semenza GL: Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. Annu Rev Cell Dev Biol. 1999, 15: 551-578. 10.1146/annurev.cellbio.15.1.551.

4. Harris AL: Hypoxia – a key regulatory factor in tumour growth. Nat Rev Cancer. 2002, 2: 38-47. 10.1038/nrc704.

5. Helczynska K, Kronblad A, Jogi A, Nilsson E, Beckman S, Landberg G, Pahlman S: Hypoxia promotes a dedifferentiated phenotype in ductal breast carcinoma in situ. Cancer Res. 2003, 63: 1441-1444.

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