Total saponin from Anemone flaccida Fr. Schmidt abrogates osteoclast differentiation and bone resorption via the inhibition of RANKL-induced NF-κB, JNK and p38 MAPKs activation-Reference-Cited by-同舟云学术

Total saponin from Anemone flaccida Fr. Schmidt abrogates osteoclast differentiation and bone resorption via the inhibition of RANKL-induced NF-κB, JNK and p38 MAPKs activation

Published:2015-03-15 Issue:1 Volume:13 Page:
ISSN:1479-5876
Container-title:Journal of Translational Medicine
language:en
Short-container-title:J Transl Med

Author:

Kong Xiangying,Wu Wenbin,Yang Yue,Wan Hongye,Li Xiaomin,Zhong Michun,Zhao Hongyan,Su Xiaohui,Jia Shiwei,Ju Dahong,Lin Na

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://link.springer.com/content/pdf/10.1186/s12967-015-0440-1.pdf

Reference43 articles.

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3. Cully M. Rheumatoid arthritis: Uncoupling bone and cartilage destruction. Nat Rev Rheumatol. 2013;9:446.

4. Ochi S, Shinohara M, Sato K, Gober HJ, Koga T, Kodama T, et al. Pathological role of osteoclast costimulation in arthritis-induced bone loss. Proc Natl Acad Sci U S A. 2007;104:11394–9.

5. Broadhead ML, Clark JC, Dass CR, Choong PF, Myers DE. Therapeutic targeting of osteoclast function and pathways. Expert Opin Ther Targets. 2011;15:169–81.

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