Loss of heterozygosity related to TMB and TNB may predict PFS for patients with SCLC received the first line setting-Reference-Cited by-同舟云学术

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Loss of heterozygosity related to TMB and TNB may predict PFS for patients with SCLC received the first line setting

Published:2021-09-08 Issue:1 Volume:19 Page:
ISSN:1479-5876
Container-title:Journal of Translational Medicine
language:en
Short-container-title:J Transl Med

Author:

Zhang Chenyue,Wang Kai,Wang Haiyong

Funder

Taishan Scholar Foundation of Shandong Province

Academic promotion program of Shandong First Medical University

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

https://link.springer.com/content/pdf/10.1186/s12967-021-03019-6.pdf

Reference6 articles.

1. Zhang X, Sjöblom T. Targeting loss of heterozygosity: a novel paradigm for cancer therapy. Pharmaceuticals. 2021;14(1):57.

2. Tapial S, García JL, Corchete L, Holowatyj AN, Pérez J, Rueda D, Urioste M, González-Sarmiento R, Perea J. Copy neutral loss of heterozygosity (cnLOH) patterns in synchronous colorectal cancer. Eur J Hum Genet. 2021;29(4):709–13.

3. Orlando EJ, Han X, Tribouley C, et al. Genetic mechanisms of target antigen loss in CAR19 therapy of acute lymphoblastic leukemia. Nat Med. 2018;24(10):1504–6.

4. Rodig SJ, Gusenleitner D, Jackson DG, et al. MHC proteins confer differential sensitivity to CTLA-4 and PD-1 blockade in untreated metastatic melanoma. Sci Transl Med. 2018;10(450):eaar3342.

5. Dawkins JBN, Webster RM. The small-cell lung cancer drug market. Nat Rev Drug Discov. 2020;19(8):507–8.

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