Prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda: cross-sectional, population-based study

Author:

Mubangizi VincentORCID,Maling Samuel,Obua Celestino,Tsai Alexander C.

Abstract

Abstract Background There is a paucity of data on the prevalence and correlates of Alzheimer’s disease and related dementias in sub-Saharan Africa. The aim of the study was to estimate the prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda. Methods We conducted a cross-sectional, population-based study in a rural region of southwestern Uganda. The Brief Community Screening Instrument for Dementia was administered to a multi-stage area probability sample of 400 people aged 60 years and over. Multivariable logistic regression was used to estimate correlates of probable dementia. Results Overall, 80 (20%) of the sample screened positive for dementia. On multivariable regression, we estimated the following correlates of probable dementia: age (adjusted odds ratio [AOR], 1.02 per year; 95% confidence interval [CI], 1.10–1.03, p<0.001), having some formal education (AOR, 0.57; 95% CI, 0.41–0.81, p = 0.001), exercise (AOR, 0.44; 95% CI, 0.27–0.72, p = 0.001), and having a ventilated kitchen (AOR, 0.43; (95% CI, 0.24–0.77, p = 0.001). Conclusions In this population-based sample of older-age adults in rural Uganda, nearly one-fifth screened positive for dementia.

Funder

Fogarty International Center and the National Institute on Aging of the U.S. National Institutes of Health

Publisher

Springer Science and Business Media LLC

Subject

Geriatrics and Gerontology

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