Author:
Meng Lingbing,Xu Ruofan,Li Jianyi,Hu Jiabin,Xu Hongxuan,Wu Dishan,Hu Xing,Zeng Xuezhai,Zhang Qiuxia,Li Juan,Liu Deping
Abstract
Abstract
Background
Chronic diseases, such as heart disease, cancer, and diabetes, are the leading causes of death and disability. Loneliness is linked to a greater risk of chronic disease. However, the lack of loneliness may change this relationship.
Methods
The 4th Survey of the Aged Population in Urban and Rural China (SSAPUR) was performed. 222,179 people over 60 years old were recruited. Chronic disease was defined by self-reported tumble incidents using the fourth SSAPUR questionnaire. We found that the residuals were well normally distributed. Subsequently, we analyzed the association between each studied factor and chronic disease by univariate logistic regression analysis. Finally, we stratified the population by age, gender, and urban and rural.
Results
77,448 individuals experienced loneliness, while 137,593 did not. Loneliness correlated significantly with urban-rural classification, age, and gender (P < 0.001). There was a significant association between chronic diseases and loneliness (P < 0.05). Compared to lonely individuals, those with low level of loneliness had a lower incidence of gastric diseases (OR = 0.752, 95% CI, 0.736–0.769, P < 0.001), osteoarthritis (OR = 0.685, 95% CI, 0.673–0.697, P < 0.001), chronic obstructive pulmonary disease (COPD) (OR = 0.678, 95% CI, 0.659–0.698, P < 0.001), asthma (OR = 0.608, 95% CI, 0.583–0.633, P < 0.001), malignant tumors (OR = 0.892, 95% CI, 0.822–0.968, P = 0.006), and reproductive system diseases (OR = 0.871, 95% CI, 0.826–0.918, P < 0.001).
Conclusion
In summary, loneliness is an important risk factor in the occurrence and development of chronic diseases in the elderly in China, and it has adverse effects on hypertension, stomach disease, cataract or glaucoma, osteoarthrosis, chronic lung disease, asthma, malignant tumor, and reproductive system diseases.
Funder
National Key Research and Development Program of China
Chinese Academy of Medical Sciences, CAMS Innovation Fund for Medical Sciences
National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC