Diagnosis and management of individuals with Fetal Valproate Spectrum Disorder; a consensus statement from the European Reference Network for Congenital Malformations and Intellectual Disability

Author:

Clayton-Smith JillORCID,Bromley Rebecca,Dean John,Journel Hubert,Odent Sylvie,Wood Amanda,Williams Janet,Cuthbert Verna,Hackett Latha,Aslam Neelo,Malm Heli,James Gregory,Westbom Lena,Day Ruth,Ladusans Edmund,Jackson Adam,Bruce Iain,Walker Robert,Sidhu Sangeet,Dyer Catrina,Ashworth Jane,Hindley Daniel,Diaz Gemma Arca,Rawson Myfanwy,Turnpenny Peter

Funder

CHAFEA

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Genetics(clinical),General Medicine

Reference115 articles.

1. Dalens B, Raynaud EJ, Gaulme J. Teratogenicity of valproic acid. J Pediatr. 1980;97(2):332–3.

2. New measures to avoid valproate exposure in pregnancy endorsed. European Medicines Agency. 2018: EMA/145600/2018 Available from. https://www.ema.europa.eu/documents/referral/valproate-article-31-referral-new-measures-avoid-valproate-exposure-pregnancy-endorsed_en-0.pdf . Accessed 31 May 2018.

3. Marson AG, Al-Kharusi AM, Alwaidh M, Appleton R, Baker GA, Chadwick DW, et al. The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial. Lancet. 2007;369(9566):1016–26.

4. Robert E, Guibaud P. Maternal valproic acid and congenital neural tube defects. Lancet. 1982;2:1282–3.

5. Robert E, Rosa F. Valproate and birth defects. Lancet. 1983;2(8359):1142.

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