Massive intestinal ischemia, a rare complication of oral contraceptive-induced mesenteric venous thrombosis: a case report and review of literature

Author:

Efremidou Eleni I,Kouklakis George,Tsirogianni Olga,Courcoutsakis Nikolaos,Manolas Konstantinos J,Liratzopoulos Nikolaos

Abstract

Abstract Intestinal necrosis and perforation is a clinical and pathological presentation of the infrequently seen mesenteric venous thrombosis in women using oral contraceptives. We report a case of a previously healthy 31-year-old female patient, who presented with a 3-day history of abdominal pain. Although chest and abdomen radiographs showed small bowel obstruction, conservative treatment failed and the patient developed peritonism. Contrast-enhanced Tomography of the abdomen revealed free air associated with dilated and thickened small bowel. A laparotomy was performed and segmental resection of both small and large bowel was required. The pathological examination showed intestinal ischemia and mesenteric venous thrombosis. There were no further predisposing factors and mesenteric venous thrombosis was ascribed to oral contraceptives.

Publisher

Springer Science and Business Media LLC

Subject

General Medicine

Reference9 articles.

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2. Koh KS, Danzinger RG: Massive intestinal infraction in young women: complication of use of oral contraceptives?. Can Med Assoc J. 1977, 116: 513-515.

3. Hassan HA: Oral contraceptive-included mesenteric venous thrombosis with resultant intestinal ischemia. J Cl Gastroenterology. 1999, 29: 90-95. 10.1097/00004836-199907000-00023.

4. Voora D, Vijayan A: Mesenteric vein thrombosis associated with intravaginal contraceptives: a case report and a review of the literature. J Thromb Thrombolysis. 2003, 15: 105-108. 10.1023/B:THRO.0000003323.80742.4d.

5. Greig JD: Oral contraceptives and intestinal ischemia. Journal of the Royal College of General Practitioners. 1989, 39: 76.

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