Heartworm adulticide treatment: a tropical perspective

Author:

Dantas-Torres Filipe,Ketzis Jennifer,Pérez Tort Gabriela,Mihalca Andrei Daniel,Baneth Gad,Otranto Domenico,Watanabe Malaika,Linh Bui Khanh,Inpankaew Tawin,Borrás Pablo,Arumugam Sangaran,Penzhorn Barend Louis,Ybañez Adrian Patalinghug,Irwin Peter,Traub Rebecca J.

Abstract

AbstractDirofilaria immitis (the canine heartworm) is widespread in the tropics, with prevalence surpassing 30% in high-risk areas. In addition to the suitable climatic conditions that favour mosquito abundance and filarial larva development, there is low compliance with the recommended year-round use of preventives in these transmission hotspots. This represents a major concern, considering that melarsomine (first-line heartworm adulticide) is unavailable in several tropical countries, resulting in the so-called slow-kill protocol being the only available adulticide treatment option. In this article, the members of TroCCAP (Tropical Council for Companion Animal Parasites) review the current distribution of heartworm in the tropics and the availability of melarsomine, and discuss alternatives for the management of heartworm infections in dogs. Graphical Abstract

Publisher

Springer Science and Business Media LLC

Subject

Infectious Diseases,Parasitology

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