Author:
Liu Pengbo,Lu Liang,Jiang Jinyong,Guo Yuhong,Yang Mingdong,Liu Qiyong
Abstract
Abstract
Background
Aedes aegypti, the vector of dengue fever, was first reported in Yunnan in 2002. Now, this species is found in nine counties in border areas of south-west Yunnan. Related dengue fever outbreaks have been reported since 2013. The population genetics of Ae. aegypti in these areas were studied to explain the expansion history of this species.
Methods
Fifteen natural populations of Ae. aegypti were sampled from six counties of Yunnan, and two laboratory populations from Guangdong and Hainan were also included in this study. A total of 12 microsatellite loci and three mitochondrial genes were analysed.
Results
The results indicate that Ae. aegypti populations from Yunnan show similar genetic diversity. The 17 populations could be divided into three groups: the first group included populations from Longchuan, Ruili and Gengma, which are located in the southwest of Yunnan; the second group included populations from Jinghong and Menghai, in the south of Yunnan; and the third group included populations from Mengla and the two laboratory populations from Guangdong and Hainan. Both microsatellite and mtDNA data revealed that the genetic relationships of the populations corresponded to their geographic relationships.
Conclusions
The results suggested that the expansion of Ae. aegypti from northern Myanmar and Laos to southern and southwestern Yunnan was a natural process. The effect of human activity on expansion was not obvious. Surveillance efforts should still be focused on border areas where Ae. aegypti does not occur, and a powerful control strategy should be applied to prevent outbreaks of dengue fever.
Funder
Ministry of Science and Technology of the People's Republic of China
Publisher
Springer Science and Business Media LLC
Subject
Infectious Diseases,Parasitology
Reference57 articles.
1. Tatem AJ, Hay SI, Rogers DJ. Global traffic and disease vector dispersal. Proc Natl Acad Sci USA. 2006;103:6242.
2. World Health Organization. Special programme for research, training in tropical diseases. Dengue: guidelines for diagnosis, treatment, prevention and control. Geneva: World Health Organization; 2009.
3. Bhatt S, Gething PW, Brady OJ, Messina JP, Farlow AW, Moyes CL, et al. The global distribution and burden of dengue. Nature. 2013;496:504–7.
4. WHO. Dengue control/What is dengue? Geneva: World Health Organization; 2019. https://www.who.int/denguecontrol/disease/en/. Accessed 15 Sept 2019.
5. Lu B. Fauna Sinica, Insecta Vol. 9, Diptera: Culicidae II, vol. 8. Beijing: Science Press; 1997.
Cited by
9 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献