Systematic review and meta-analysis of bovine cysticercosis in Brazil: current knowledge and way forward

Abstract

Abstract Background Taenia saginata taeniosis/cysticercosis has been well studied in several countries. Brazil is one of the most important beef exporting countries and has one of the highest cattle population size in the world. In this country, bovine cysticercosis (BCC) remains the most frequent reported zoonosis detected during post-mortem inspection, resulting in costs for the beef sector and public health. We performed a systematic literature review regarding data about BCC epidemiology in Brazil and meta-analyses for its prevalence in different administrative regions and the distribution over time, and based on this discussed possible control strategies. Methods A systematic review was conducted to obtain data about BCC in Brazil using the words “bovine cysticercosis” and “Brazil” to construct the search phrase. The inclusion criteria used to select articles were: (i) published from 2000 to 2018; (ii) full text available online in Portuguese or English; and (iii) contain information at least regarding one of the following aspects of BCC in Brazil: prevalence, incidence, spatial distribution, risk-factors, economic burden and measures for control. Results A set of 42 articles was included, covering the prevalence of BCC in Brazil, ranging between 0.01–18.75%. Prevalence results of 40 articles were included in a meta-analysis per administrative region. The highest prevalence was found in the South (3.4%; 95% CI: 2.0–5.2%), followed by the Southeast (2.7%; 95% CI: 1.9–3.6%), Northeast (1.5%; 95% CI: 0.6–2.7%), Central-western (0.9%; 95% CI: 0.3–1.7%) and North (0.0%; 95% CI: 0.0–0.6%) region. In addition, a reduction in prevalence over time was observed in all the evaluated states except for Alagoas and Pará. Conclusions Besides the large availability of data, a critical lack of information about BCC epidemiology remains in Brazil. Nevertheless, the available data on prevalence, high risk-areas and risk factors should contribute to a better understanding of transmission and the formulation of recommendations for control. A One Health approach will be required to reduce T. saginata taeniosis/cysticercosis prevalence and the consequent economic burden for the beef sector in Brazil, one of the most important beef exporters in the world.