DOPA-decarboxylase is elevated in CSF, but not plasma, in prodromal and de novo Parkinson’s disease
Author:
Funder
Knut och Alice Wallenbergs Stiftelse
NHLBI Division of Intramural Research
Science for Life Laboratory
Kommunfullmäktige, Stockholms Stad
Publisher
Springer Science and Business Media LLC
Link
https://link.springer.com/content/pdf/10.1186/s40035-024-00421-0.pdf
Reference8 articles.
1. Bloem BR, Okun MS, Klein C. Parkinson’s disease. Lancet. 2021;397(10291):2284–303.
2. Siderowf A, Concha-Marambio L, Lafontant DE, Farris CM, Ma Y, Urenia PA, et al. Assessment of heterogeneity among participants in the Parkinson’s progression markers initiative cohort using α-synuclein seed amplification: a cross-sectional study. Lancet Neurol. 2023;22(5):407–17.
3. Paslawski W, Khosousi S, Hertz E, Markaki I, Boxer A, Svenningsson P. Large-scale proximity extension assay reveals CSF midkine and DOPA decarboxylase as supportive diagnostic biomarkers for Parkinson’s disease. Transl Neurodegener. 2023;12(1):42.
4. Pereira JB, Kumar A, Hall S, Palmqvist S, Stomrud E, Bali D, et al. DOPA decarboxylase is an emerging biomarker for Parkinsonian disorders including preclinical Lewy body disease. Nat Aging. 2023;3(10):1201–9.
5. Del Campo M, Vermunt L, Peeters CFW, Sieben A, Hok AHYS, Lleó A, et al. CSF proteome profiling reveals biomarkers to discriminate dementia with Lewy bodies from Alzheimer’s disease. Nat Commun. 2023;14(1):5635.
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