Modulating the catalytic activity of AMPK has neuroprotective effects against α-synuclein toxicity-Reference-Cited by-同舟云学术

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Modulating the catalytic activity of AMPK has neuroprotective effects against α-synuclein toxicity

Published:2017-11-03 Issue:1 Volume:12 Page:
ISSN:1750-1326
Container-title:Molecular Neurodegeneration
language:en
Short-container-title:Mol Neurodegeneration

Author:

Bobela Wojciech,Nazeeruddin Sameer,Knott Graham,Aebischer Patrick,Schneider Bernard L.

Funder

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Merck Serono EPFL Alliance

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Neurology (clinical),Molecular Biology

Link

http://link.springer.com/content/pdf/10.1186/s13024-017-0220-x.pdf

Reference78 articles.

1. Polymeropoulos MH, Lavedan C, Leroy E, Ide SE, Dehejia A, Dutra A, Pike B, Root H, Rubenstein J, Boyer R, et al. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science. 1997;276(5321):2045–7.

2. Spillantini MG, Schmidt ML, Lee VM, Trojanowski JQ, Jakes R, Goedert M. Alpha-synuclein in Lewy bodies. Nature. 1997;388(6645):839–40.

3. Dettmer U, Selkoe D, Bartels T. New insights into cellular alpha-synuclein homeostasis in health and disease. Curr Opin Neurobiol. 2015;36:15–22.

4. Lashuel HA, Overk CR, Oueslati A, Masliah E. The many faces of alpha-synuclein: from structure and toxicity to therapeutic target. Nat Rev Neurosci. 2013;14(1):38–48.

5. Vila M, Przedborski S. Genetic clues to the pathogenesis of Parkinson's disease. Nat Med. 2004;10(Suppl):S58–62.

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