A brain-penetrant triazolopyrimidine enhances microtubule-stability, reduces axonal dysfunction and decreases tau pathology in a mouse tauopathy model-Reference-Cited by-同舟云学术

A brain-penetrant triazolopyrimidine enhances microtubule-stability, reduces axonal dysfunction and decreases tau pathology in a mouse tauopathy model

Published:2018-11-07 Issue:1 Volume:13 Page:
ISSN:1750-1326
Container-title:Molecular Neurodegeneration
language:en
Short-container-title:Mol Neurodegeneration

Author:

Zhang Bin,Yao Yuemang,Cornec Anne-Sophie,Oukoloff Killian,James Michael J.,Koivula Pyry,Trojanowski John Q.,Smith Amos B.,Lee Virginia M.-Y.,Ballatore Carlo,Brunden Kurt R.^ORCID

Funder

National Institute on Aging

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Neurology (clinical),Molecular Biology

Link

http://link.springer.com/content/pdf/10.1186/s13024-018-0291-3.pdf

Reference69 articles.

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2. Ballatore C, Lee VMY, Trojanowski JQ. Tau-mediated neurodegeneration in Alzheimer’s disease and related disorders. Nat Rev Neurosci. 2007;8:663–72.

3. Huang Y, Mucke L. Alzheimer mechanisms and therapeutic strategies. Cell. 2012;148:1204–22.