MicroRNA profile changes in human immunodeficiency virus type 1 (HIV-1) seropositive individuals-Reference-Cited by-同舟云学术

MicroRNA profile changes in human immunodeficiency virus type 1 (HIV-1) seropositive individuals

Published:2008-12 Issue:1 Volume:5 Page:
ISSN:1742-4690
Container-title:Retrovirology
language:en
Short-container-title:Retrovirology

Author:

Houzet Laurent,Yeung Man Lung,de Lame Valery,Desai Dhara,Smith Stephen M,Jeang Kuan-Teh

Abstract

Abstract MicroRNAs (miRNAs) play diverse roles in regulating cellular and developmental functions. We have profiled the miRNA expression in peripheral blood mononuclear cells from 36 HIV-1 seropositive individuals and 12 normal controls. The HIV-1-positive individuals were categorized operationally into four classes based on their CD4+ T-cell counts and their viral loads. We report that specific miRNA signatures can be observed for each of the four classes.

Publisher

Springer Science and Business Media LLC

Subject

Infectious Diseases,Virology

Link

https://link.springer.com/content/pdf/10.1186/1742-4690-5-118.pdf

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