Treatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients-Reference-Cited by-同舟云学术

Treatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients

Published:2012-10-03 Issue:1 Volume:9 Page:
ISSN:1742-4690
Container-title:Retrovirology
language:en
Short-container-title:Retrovirology

Author:

Theys Kristof,Deforche Koen,Vercauteren Jurgen,Libin Pieter,van de Vijver David AMC,Albert Jan,Åsjö Birgitta,Balotta Claudia,Bruckova Marie,Camacho Ricardo J,Clotet Bonaventura,Coughlan Suzie,Grossman Zehava,Hamouda Osamah,Horban Andrzei,Korn Klaus,Kostrikis Leondios G,Kücherer Claudia,Nielsen Claus,Paraskevis Dimitrios,Poljak Mario,Puchhammer-Stockl Elisabeth,Riva Chiara,Ruiz Lidia,Liitsola Kirsi,Schmit Jean-Claude,Schuurman Rob,Sönnerborg Anders,Stanekova Danica,Stanojevic Maja,Struck Daniel,Van Laethem Kristel,Wensing Annemarie MJ,Boucher Charles AB,Vandamme Anne-Mieke

Publisher

Springer Science and Business Media LLC

Subject

Infectious Diseases,Virology

Link

http://link.springer.com/content/pdf/10.1186/1742-4690-9-81.pdf

Reference47 articles.

1. Vandamme AM, Van Laethem K, De Clercq E: Managing resistance to anti-HIV drugs: an important consideration for effective disease management. Drugs. 1999, 57: 337-361. 10.2165/00003495-199957030-00006.

2. Martinez-Picado J, Martinez MA: HIV-1 reverse transcriptase inhibitor resistance mutations and fitness: a view from the clinic and ex vivo. Virus Res. 2008, 134: 104-123. 10.1016/j.virusres.2007.12.021.

3. Verhofstede C, Wanzeele FV, Van Der Gucht B, De Cabooter N, Plum J: Interruption of reverse transcriptase inhibitors or a switch from reverse transcriptase to protease inhibitors resulted in a fast reappearance of virus strains with a reverse transcriptase inhibitor-sensitive genotype. AIDS. 1999, 13: 2541-2546. 10.1097/00002030-199912240-00007.

4. Wensing AM, van de Vijver, Angarano G, Asjö B, Balotta C, Boeri E, Camacho R, Chaix ML, Costagliola D, De Luca A, Derdelinckx I, Grossman Z, Hamouda O, Hatzakis A, Hemmer R, Hoepelman A, Horban A, Korn K, Kücherer C, Leitner T, Loveday C, MacRae E, Maljkovic I, de Mendoza C, Meyer L, Nielsen C, Op de Coul, Ormaasen V, Paraskevis D, Perrin L, et al: Prevalence of drug-resistant HIV-1 variants in untreated individuals in Europe: implications for clinical management. J Infect Dis. 2005, 192: 958-966. 10.1086/432916.

5. Wensing A, Vercauteren J, van de Vijver, Albert J, Åsjö B, Claudia B, Camacho R, Coughlan S, Grossman Z, Horban A, Kücherer C, Nielsen C, Paraskevis D, Loke W, Poggensee G, Riva C, Ruiz L, Schmit J, Schuurman R, Salminen M, Sonnerborg A, Stanojevic M, Struck D, Vandamme A, Boucher CA: Transmission of drug-resistant HIV-1 in Europe remains limited to single classes. AIDS. 2008, 22: 625-635.

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