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Identification of potential therapeutic targets for nonischemic cardiomyopathy in European ancestry: an integrated multiomics analysis

  • Published:2024-09-12 Issue:1 Volume:23 Page:
  • ISSN:1475-2840
  • Container-title:Cardiovascular Diabetology
  • language:en
  • Short-container-title:Cardiovasc Diabetol

Author:

Shi KaijiaORCID,Chen XuORCID,Zhao Yangyang,Li Peihu,Chai Jinxuan,Qiu Jianmin,Shen ZhihuaORCID,Guo JunliORCID,Jie WeiORCID

Funder

Innovative Research Projects for Graduate Students in Hainan Province

National Natural Science Foundation of China

Cardiovascular Disease Research Science Innovation Group of Hainan Medical University

the Innovational Fund for Scientific and Technological Personnel of Hainan Province

Hainan Key Research and Development Project

Publisher

Springer Science and Business Media LLC

Reference43 articles.

1. Maron BJ, Towbin JA, Thiene G, Antzelevitch C, Corrado D, Arnett D, Moss AJ, Seidman CE, Young JB. Contemporary definitions and classification of the cardiomyopathies: an American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention. Circulation. 2006;113(14):1807–16.

2. Zhao Y, Quan E, Zeng T, Huang Z, Luo Y, Peng L, Li S, Liu J, Chong Y, Cao H. Type 1 diabetes, its complications, and non-ischemic cardiomyopathy: a mendelian randomization study of European ancestry. Cardiovasc Diabetol. 2024;23(1):31.

3. Nikolova AP, Hitzeman TC, Baum R, Caldaruse AM, Agvanian S, Xie Y, Geft DR, Chang DH, Moriguchi JD, Hage A, et al. Association of a Novel Diagnostic Biomarker, the plasma Cardiac bridging integrator 1 score, with heart failure with preserved ejection Fraction and Cardiovascular hospitalization. JAMA Cardiol. 2018;3(12):1206–10.

4. Sun BB, Chiou J, Traylor M, Benner C, Hsu YH, Richardson TG, Surendran P, Mahajan A, Robins C, Vasquez-Grinnell SG, et al. Plasma proteomic associations with genetics and health in the UK Biobank. Nature. 2023;622(7982):329–38.

5. Zhang J, Dutta D, Köttgen A, Tin A, Schlosser P, Grams ME, Harvey B, Yu B, Boerwinkle E, Coresh J, et al. Plasma proteome analyses in individuals of European and African ancestry identify cis-pQTLs and models for proteome-wide association studies. Nat Genet. 2022;54(5):593–602.
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