Author:
Chen Jun,Tang Hui,Zhang Ding,Tang Yuqi,Li Wenjie,Liu Gui,Liu Binjie
Abstract
Abstract
Background
Pemphigus vulgaris (PV) is a kind of rare and severe autoimmune bullous disease. In this case, the specificity of oral PV lies in the clinical manifestations of a single palatal ulcer, and no blisters were found in the oral mucosa. This case provides a powerful reference for dentists diagnosing and treating oral PV with atypical clinical presentations.
Case presentation
A 54 years old female patient presented with a non-healing palatal gingival ulcer for over three months. By histopathological H&E staining and the direct immunofluorescence (DIF) test, the final diagnosis was oral PV. After topical glucocorticoid therapy, the affected area was cured.
Conclusions
In patients with prolonged erosion of the skin or oral mucosa, even if complete blisters are not visible, the physician should consider autoimmune bullous diseases and pay attention to avoid diagnostic defects.
Funder
clinical medical boot technology innovation project of Hunan Province
the Health and Family Planning Commission of Hunan Province
Natural Science Foundation of Hunan Province
Science and Technology Bureau of Changsha
Publisher
Springer Science and Business Media LLC