Author:
Konold Timm,Davis Andrew,Bone Gemma,Bracegirdle John,Everitt Sharon,Chaplin Melanie,Saunders Ginny C,Cawthraw Saira,Simmons Marion M
Abstract
Abstract
Background
Atypical scrapie is a recently recognised form of transmissible spongiform encephalopathy of sheep that differs from classical scrapie in its neuropathological and biochemical features. Most cases are detected in apparently healthy sheep and information on the clinical presentation is limited.
Case presentation
This report describes the clinical findings in two sheep notified as scrapie suspects and confirmed as atypical scrapie cases by immunohistochemistry and Western immunoblotting. Although both sheep displayed signs suggestive of a cerebellar dysfunction there was considerable variation in the individual clinical signs, which were similar to classical scrapie.
Conclusion
Any sheep presenting with neurological gait deficits should be assessed more closely for other behavioural, neurological and physical signs associated with scrapie and their presence should lead to the suspicion of scrapie.
Publisher
Springer Science and Business Media LLC
Subject
General Veterinary,General Medicine
Cited by
43 articles.
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