Carcinogenic effect of potassium octatitanate (POT) fibers in the lung and pleura of male Fischer 344 rats after intrapulmonary administration

Author:

Abdelgied Mohamed,El-Gazzar Ahmed M.,Alexander William T.,Numano Takamasa,Iigou Masaaki,Naiki-Ito Aya,Takase Hiroshi,Hirose Akihiko,Taquahashi Yuhji,Kanno Jun,Abdelhamid Mona,Abdou Khaled Abbas,Takahashi Satoru,Alexander David B.ORCID,Tsuda Hiroyuki

Funder

Ministry of Health, Labour and Welfare

Cultural Affairs and Missions Sector, Ministry of Higher Education

Long Range Research Initiative (LRI) by the Japan Chemical Industry Association

YOG Specified Nonprofit Corporation

Association for the Promotion of Research on Risk Assessment

Egyptian Cultural Affairs and Missions Sector

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Reference26 articles.

1. Yamato H, Morimoto Y, Tsuda T, Ogami A, Oyabu T, Ishimatsu S, et al. Clearance of inhaled potassium Octatitanate whisker from rat lungs. J Occup Health. 2002;44(1):34–9.  https://doi.org/10.1539/joh.44.34 .

2. Donaldson K, Murphy F, Schinwald A, Duffin R, Poland CA. Identifying the pulmonary hazard of high aspect ratio nanoparticles to enable their safety-by-design. Nanomedicine (Lond). 2011;6(1):143–56. https://doi.org/10.2217/nnm.10.139 http://www.ncbi.nlm.nih.gov/pubmed/21182425 .

3. Stanton MF, Layard M. The carcinogenicity of fibrous minerals. In: Workshop on Asbestos: definitions and measurement methods. National Bureau of standards special publication 506; 1978. p. 143–51. https://ia801405.us.archive.org/6/items/proceedingsofwor506grav/proceedingsofwor506grav.pdf Accessed 08 Dec 2018.

4. Stanton MF, Layard M, Tegeris A, Miller E, May M, Morgan E, et al. Relation of particle dimension to carcinogenicity in amphibole asbestoses and other fibrous minerals. J Natl Cancer Inst. 1981;67(5):965–75 http://www.ncbi.nlm.nih.gov/pubmed/6946253 .

5. Lee KP, Barras CE, Griffith FD, Waritz RS. Pulmonary response and transmigration of inorganic fibers by inhalation exposure. Am J Pathol. 1981;102(3):314–23 https://www.ncbi.nlm.nih.gov/pubmed/7212016 .

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