Author:
Yu Yong,Luo Bangan,Qin Lulu,Gong Hongjie,Chen Yijia
Abstract
Abstract
Background
The HIV/AIDS (human immunodeficiency virus/acquired immune deficiency syndrome) remains a global threat to health. Suicidal ideation has been a serious public health problem among people living with HIV (PLWH). However, the suicide prevention mechanism among PLWH still unclear. This study aims to analyze the suicidal ideation and its related factors in PLWH, and further explore the relationships between suicidal ideation and depression, anxiety and perceived social support.
Methods
This is a cross-sectional study. A total of 1146 PLWH were investigated by the general information questionnaire, the perceived social support scale (PSSS), the Beck scale for suicide ideation of Chinese version (BSI-CV), the generalized anxiety disorder scale-2 (GAD-2) and the patient health questionnaire-2 (PHQ-2) though the WeChat in China in 2018. By using statistical description and the binary unconditional logistic regression, we assessed the incidence of suicidal ideation and its related factors in PLWH. Besides, the intermediary effect of social support between anxiety, depression and suicidal ideation were explored by the stepwise test and Bootstrap method.
Results
The incidence of suicide ideation was 54.0% (619/1146) among the PLWH in the last week or during the most serious depression. Binary logistic regression analysis results showed that the PLWH who with short time for HIV positive diagnosis (aOR (adjusted odd ratio) = 1.754, 95% CI (confidence interval):1.338–2.299), low monthly income (aOR = 1.515, 95%CI:1.098–2.092), other chronic diseases except HIV (aOR = 1.555, 95%CI:1.134–2.132), irregular lovers (aOR = 1.369, 95%CI:1.021–1.837), anxiety (aOR = 2.711, 95%CI:1.767–4.161), depression (aOR = 1.614, 95%CI:1.078–2.417), low PSSS (aOR = 2.139, 95%CI:1.345–3.399) had high risk of suicide ideation.The social support played a mediating role between the anxiety (the mediating effect accounted for 30.43% of the total effect), depression (the mediating effect accounted for 23.76% of the total effect) and the suicide ideation among PLWH.
Conclusion
The incidence of suicide ideation of PLWH was high. Anxiety, depression, and social support are the key factors of suicide ideation of PLWH. Social support plays a partial mediating role between anxiety, depression and suicidal ideation, which provides a new approach for prevention of suicidal ideation in PLWH and should be known widely for people to prevent suicide.
Funder
Special Funding Project for High-level Innovation Teams and Outstanding Scholars Plan of Guangxi Colleges and University
National Ethnic Affairs Commission of the People`s Republic of China
The Scientific Project of Hunan Health Commission
The Medical Humanities and Social Sciences Interdisciplinary Research Project of Hunan Normal University
Innovation and Entrepreneurship Training Program for College Students in Hunan Province
the Scientific research project of Hunan Education Department
Publisher
Springer Science and Business Media LLC
Subject
General Psychology,General Medicine
Reference34 articles.
1. UNAIDS. AIDS by the numbers. 2020. http://www.unaids.org/. Accessed 2 Mar 2020.
2. National Health Commission of the People's Republic of China. Epidemic situation of notifiable infectious diseases in October 2020 of China. 2020. http://www.nhc.gov.cn/cms-search/xxgk/getManuscriptXxgk. Accessed 3 Nov 2020.
3. Clifford DB, Evans S, Yang Y, Acosta EP, Ribaudo H, Gulick RM, A5097s Study Team. Impact of efavirenz on neuropsychological performance and symptoms in HIV-infected individuals. Ann Intern Med. 2005;143(10):714–721.
4. Wu YL, Yang H, Wang J, Yao H, Zhao X, Chen J, Ding XX, Zhang HB, Bi P, Sun YH. Prevalence of suicidal ideation and associated factors among HIV-positive MSM in Anhui, China. Int J STD AIDS. 2015;26(7):496–503.
5. Kuai Q, Wang Y, Gao F, Qi Y, Wang R, Wang Y, Lu X, Zhao Y, Nie G, He M, Zhou H, Jiang X, Ren S, Yu Q. Peptide self-assembly nanoparticles loaded with panobinostat to activate latent human immunodeficiency virus. J Biomed Nanotechnol. 2019;15(5):979–92.
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