A systems approach for analysis of high content screening assay data with topic modeling-Reference-Cited by-同舟云学术

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A systems approach for analysis of high content screening assay data with topic modeling

Published:2013-10 Issue:S14 Volume:14 Page:
ISSN:1471-2105
Container-title:BMC Bioinformatics
language:en
Short-container-title:BMC Bioinformatics

Author:

Bisgin Halil,Chen Minjun,Wang Yuping,Kelly Reagan,Fang Hong,Xu Xiaowei,Tong Weida

Publisher

Springer Science and Business Media LLC

Subject

Applied Mathematics,Computer Science Applications,Molecular Biology,Biochemistry,Structural Biology

Link

https://link.springer.com/content/pdf/10.1186/1471-2105-14-S14-S11.pdf

Reference41 articles.

1. Watkins PB: Drug safety sciences and the bottleneck in drug development. Clin Pharmacol Ther. 2011, 89 (6): 788-790. 10.1038/clpt.2011.63.

2. Chen M, Vijay V, Shi Q, Liu Z, Fang H, Tong W: FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today. 2011, 16 (15-16): 697-703. 10.1016/j.drudis.2011.05.007.

3. O'Brien PJ, Irwin W, Diaz D, Howard-Cofield E, Krejsa CM, Slaughter MR, Gao B, Kaludercic N, Angeline A, Bernardi P: High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening. Arch Toxicol. 2006, 80 (9): 580-604. 10.1007/s00204-006-0091-3.

4. Giuliano KA, Chen YT, Taylor DL: High-content screening with siRNA optimizes a cell biological approach to drug discovery: defining the role of P53 activation in the cellular response to anticancer drugs. J Biomol Screen. 2004, 9 (7): 557-568. 10.1177/1087057104265387.

5. Vogt A, Tamewitz A, Skoko J, Sikorski RP, Giuliano KA, Lazo JS: The benzo[c]phenanthridine alkaloid, sanguinarine, is a selective, cell-active inhibitor of mitogen-activated protein kinase phosphatase-1. J Biol Chem. 2005, 280 (19): 19078-19086. 10.1074/jbc.M501467200.

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