Abstract
Abstract
Background
During multi-detector computed tomography (MDCT) of the chest, incidental breast lesions (IBLs) are occasionally encountered. Mammography remains the gold standard for the early detection of breast cancer. However, limitations exist in patients with dense breasts. Contrast spectral mammography (CESM) is widely available compared to MRI; it increases the sensitivity for breast cancer detection without decreasing the specificity.
Results
The study is a prospective study that included 113 female breast cancer patients for CT staging. One hundred and six of the patients had unilateral carcinoma and 7 of them had bilateral cancer with a total of 120 breasts evaluated. The CT findings were correlated with CESM findings regarding the multiplicity and bilaterality of the disease. The sensitivity, specificity, PPV, NPV, and accuracy of the CT in the detection of multiplicity were 97.44%, 100%, 100%, 95.45%, and 98.33%, respectively, and the sensitivity, specificity, PPV, NPV, and accuracy of the CT in the detection of bilateral disease were 68.18%, 97.96%, 88.24%, 93.20%, and 92.50%, respectively.
Conclusions
Breast cancer patients for MDCT chest as a part of their metastatic workup can omit the further need for CESM.
Publisher
Springer Science and Business Media LLC
Subject
Radiology, Nuclear Medicine and imaging
Reference16 articles.
1. Chetan A, Mack J, Chan T (2016) Breast cancer screening controversies: who, when, why, and how? Clin Imaging 40(2):279–282
2. Fallenberg EM, Dromain C, Diekmann F, Engelken F, Krohn M, Singh JM, Ingold-Heppner B, Winzer KJ, Bick U, Renz DM (2013) Contrast-enhanced spectral mammography versus MRI: initial results in detection of breast cancer and assessment of tumor size. Eur Radiol 24(1):256–264
3. Lin YP, Hsu HH, Ko KH, Chu CM, Chou YC, Chang WC, Chang TH (2016) Differentiation of malignant and benign incidental breast lesions detected by chest multidetector-row computed tomography: added value of quantitative enhancement analysis. PLoS ONE 11:e0154569
4. National Comprehensive Cancer Network (2010) Clinical practice guidelines in oncology for breast cancer V.1. National Comprehensive Cancer Network, Fort Washington
5. Morris EA, Comstock CE, Lee CH (2013) ACR BI-RADS: breast imaging reporting and data system, 5th edn. American College of Radiology, Reston
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