Stiff person syndrome presenting with sudden onset of shortness of breath and difficulty moving the right arm: a case report

Author:

Goodson Bradley,Martin Kate,Hunt Thomas

Abstract

Abstract Introduction First described in 1956, stiff person syndrome is characterized by episodes of slowly progressive stiffness and rigidity in both the paraspinal and limb muscles. Although considered a rare disorder, stiff person syndrome is likely to be under-diagnosed due to a general lack of awareness of the disease in the medical community. Case presentation A 27-year-old Hispanic woman presented to our emergency department with a sudden onset of shortness of breath and difficulty moving her right arm. Her physical examination was remarkable in that her abdomen was firm to palpation and her right upper extremity was rigid on passive and active ranges of motion. Her right fingers were clenched in a fist. Her electromyography findings were consistent with stiff person syndrome in the right clinical setting. Stiff person syndrome is confirmed by testing for the anti-glutamic acid decarboxylase antibody. Her test for this was positive. Conclusion Stiff person syndrome may not be a common condition. However, if disregarded in the differential diagnosis, it can lead to several unnecessary tests being carried out causing a delay in treatment. This case report reveals some of the characteristic features of stiff person syndrome with an atypical presentation.

Publisher

Springer Science and Business Media LLC

Subject

General Medicine

Reference9 articles.

1. Moersch FP, Woltman HW: Progressive fluctuating muscular rigidity and spasm ("stiff-man" syndrome): report of a case and some observations in 13 other cases. Mayo Clin Proc. 1956, 31: 421-427.

2. Lorish TR, Thorsteinsson G, Howard FM: Stiff-man syndrome updated. Mayo Clin Proc. 1989, 14: 629-636.

3. Kimura J: Electrodiagnosis in Diseases of Nerve and Muscle: Principles and Practice. 1989, Philadelphia: FA Davis, 2

4. Solimena M, Folli F, Aparisi R, Pozza G, DeCamilli P: Autoantibodies to GABAergic neurons and pancreatic beta cells in stiff-man syndrome. N Engl J Med. 1990, 322: 1555-1560.

5. Dalakas MC, Fujii M, Li M, McElroy B: The clinical spectrum of anti-GAD antibody-positive patients with stiff-person syndrome. Neurology. 2000, 55: 1531-1535.

Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Dyspnea in Patients with Stiff-Person Syndrome;The American Journal of the Medical Sciences;2019-10

2. A Stiff Person Case Admitted Phsysical Medicine and Rehabilitation Outpatient Clinic with Low Back Pain;Türkiye Fiziksel Tip ve Rehabilitasyon Dergisi;2015-09-30

3. Phenotype-Specific Diagnosis of Functional (Psychogenic) Movement Disorders;Current Neurology and Neuroscience Reports;2015-04-23

4. Spasmodic dysphonia like presentation of stiff person syndrome;Journal of Neurosciences in Rural Practice;2014

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3