Post-burn breast reconstruction using an artificial dermis—a long-term follow-up

Author:

Gronovich Yoav1,Maisel Lotan Adi1,Retchkiman Meir1

Affiliation:

1. Department of Plastic and Reconstructive Surgery Shaare-Zedek Medical Center 12 Beith Street Jerusalem, Israel

Abstract

Abstract Background Full thickness burns of the chest in childhood are a devastating problem that requires challenging reconstructive options. Integra is a bilaminate artificial dermis composed of shark chondroitin 6-sulfate and bovine collagen. The dermal matrix serves as a scaffold for fibroblasts and endothelial cells. Vascularization of the matrix begins after 2–3 weeks, and eventually, the matrix incorporates with the tissue to create a new dermis. The main advantage of the Integra is that the neodermis is of the same quality as a native dermis. Case presentation In this case report, we present post-burn breast reconstruction of a 12-year-old girl using Integra, with a long follow-up of 7 years. To the best of our knowledge, there is no published follow-up of breast development after reconstruction with Integra from its beginning point at the age of puberty until after the growing process has terminated. Conclusions Integra is a reliable reconstructive tool for burned breast. If done before puberty, it can help in getting normal developing tissue with satisfying esthetic results of size, shape and symmetry.

Publisher

Oxford University Press (OUP)

Subject

Critical Care and Intensive Care Medicine,Dermatology,Biomedical Engineering,Emergency Medicine,Immunology and Allergy,Surgery

Reference9 articles.

1. Burned breast reconstructive surgery with Integra dermal regeneration template;Palao;Br J Plast Surg,2003

2. A clinical trial of Integra template for diabetic foot ulcer treatment;Driver;Wound Repair Regen,2015

3. Burned breast reconstruction by expanded artificial dermal substitute;Tsoutsos;J Burn Care Res,2007

4. The use of the artificial dermis (Integra) in combination with vacuum assisted closure for reconstruction of an extensive burn scar—a case report;Leffler;J Plast Reconstr Aesthet Surg,2010

5. Long term clinical and histological analysis of Integra dermal regeneration template use and literature review of template histology;Moiemen;Plast Reconstr Surg,2010

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