The aluminium-[18F]fluoride revolution: simple radiochemistry with a big impact for radiolabelled biomolecules-Reference-Cited by-同舟云学术

The aluminium-[18F]fluoride revolution: simple radiochemistry with a big impact for radiolabelled biomolecules

Published:2021-08-26 Issue:1 Volume:6 Page:
ISSN:2365-421X
Container-title:EJNMMI Radiopharmacy and Chemistry
language:en
Short-container-title:EJNMMI radiopharm. chem.

Author:

Archibald Stephen J.,Allott Louis^ORCID

Abstract

AbstractThe aluminium-[18F]fluoride ([18F]AlF) radiolabelling method combines the favourable decay characteristics of fluorine-18 with the convenience and familiarity of metal-based radiochemistry and has been used to parallel gallium-68 radiopharmaceutical developments. As such, the [18F]AlF method is popular and widely implemented in the development of radiopharmaceuticals for the clinic. In this review, we capture the current status of [18F]AlF-based technology and reflect upon its impact on nuclear medicine, as well as offering our perspective on what the future holds for this unique radiolabelling method.

Funder

medical research council

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,Radiology Nuclear Medicine and imaging,Analytical Chemistry

Link

https://link.springer.com/content/pdf/10.1186/s41181-021-00141-0.pdf

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