Serial bone marrow transplantation reveals in vivo expression of the pCLPG retroviral vector
Author:
Publisher
Springer Science and Business Media LLC
Subject
Infectious Diseases,Virology
Link
http://link.springer.com/content/pdf/10.1186/1743-422X-7-16.pdf
Reference24 articles.
1. Nair V: Retrovirus-induced oncogenesis and safety of retroviral vectors. Curr Opin Mol Ther 2008, 10: 431-438.
2. Pike-Overzet K, Burg M, Wagemaker G, van Dongen JJ, Staal FJ: New insights and unresolved issues regarding insertional mutagenesis in X-linked SCID gene therapy. Mol Ther 2007, 15: 1910-1916. 10.1038/sj.mt.6300297
3. Challita PM, Kohn DB: Lack of expression from a retroviral vector after transduction of murine hematopoietic stem cells is associated with methylation in vivo. Proc Natl Acad Sci USA 1994, 91: 2567-2571. 10.1073/pnas.91.7.2567
4. Challita PM, Skelton D, el-Khoueiry A, Yu XJ, Weinberg K, Kohn DB: Multiple modifications in cis elements of the long terminal repeat of retroviral vectors lead to increased expression and decreased DNA methylation in embryonic carcinoma cells. J Virol 1995, 69: 748-755.
5. Hacein-Bey H, Cavazzana-Calvo M, Le Deist F, Dautry-Varsat A, Hivroz C, Riviere I, Danos O, Heard JM, Sugamura K, Fischer A, De Saint Basile G: gamma-c gene transfer into SCID X1 patients' B-cell lines restores normal high-affinity interleukin-2 receptor expression and function. Blood 1996, 87: 3108-3116.
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