Author:
Zhang Wen,Yang Shixing,Shen Quan,Liu Junfeng,Shan Tongling,Huang Fen,Ning Huibo,Kang Yanjun,Yang Zhibiao,Cui Li,Zhu Jianguo,Hua Xiuguo
Abstract
Abstract
In the present study, a genotype 4 HEV strain was identified in the fecal specimen from a seven months old infant with no symptom of hepatitis in Shanghai Children's hospital. The full capsid protein gene (ORF2) sequence of this strain was determined by RT-PCR method. Sequence analysis based on the full ORF2 sequence indicated that this HEV strain shared the highest sequence identity (97.6%) with another human HEV strain isolated from a Japanese patient who was infected by genotype 4 HEV during traveling in Shanghai. Phylogenetic analysis showed that this genotype 4 HEV was phylogenetically far from the genotype 4 HEV strain that was commonly prevalent in Shanghai swine group, suggesting that this strain may not come from swine group and not involved in zoonotic transmission in this area.
Publisher
Springer Science and Business Media LLC
Subject
Infectious Diseases,Virology
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