Author:
Jeyakumar Angeline,Shinde Vidhya,Ravindran Reshma
Abstract
Abstract
Background
Vitamin D deficiency among pregnant women is a public health concern globally. In India, individual studies report high prevalence. However, lack of national data masks the true burden. This work determined the pooled prevalence of vitamin D deficiency among pregnant women in India through a systematic review of literature and meta-analysis.
Methods
Three different search engines yielded 15 eligible articles. Study quality was assessed by 10 different criteria and summary of study quality was categorized as per Cochrane standards. Meta-analysis was performed to estimate pooled prevalence of vitamin D deficiency among healthy pregnant women and heterogeneity among selected studies. A sample of n = 4088 was used to study the pooled prevalence among pregnant women.
Results
The random effects combined estimate was 32.35% (95% CI, (12.58–117.48). High heterogeneity (tau2 = 0.39, I2 = 100%) and high risk of bias was observed among the selected studies. The test for overall effect was observed to be z = 2.54(P = 0.01).
Conclusion
Pooled estimate > 30% emphasizes the need for screening through antenatal care services and initiate preventive measures to address the deficiency.
Funder
University Grants Commission
Publisher
Springer Science and Business Media LLC
Subject
Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health,Food Science
Reference74 articles.
1. World Health Organization. Guideline: vitamin D supplementation in pregnant women.2012; Available in http://www.who.int/nutrition/publications/micronutrients/guidelines/vit_d_supp_pregnant_women/en/ Accessed December 2018.
2. Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011;96(7):1911–30. https://doi.org/10.1210/jc.2011-0385.
3. Van der Pligt P, Willcox J, Szymlek-Gay E, Murray E, Worsley A, Daly R. Associations of maternal vitamin D deficiency with pregnancy and neonatal complications in developing countries: a systematic review. Nutrients. 2018;10(5):640. https://doi.org/10.3390/nu10050640.
4. Edwards MH, Cole ZA, Harvey NC, Cooper C. The global epidemiology of vitamin D status. J Aging Res Clin Prac. 2014;3(3):148–58.
5. Vandevijvere S, Amsalkhir S, Van Oyen H, Moreno-Reyes R. High prevalence of vitamin D deficiency in pregnant women: a national cross-sectional survey. PloS one. 2012;7(8):e43868. https://doi.org/10.1371/journal.pone.0043868.
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