Severe coagulopathy caused by cefminox sodium in a liver cirrhosis patient: a case report

Author:

Wu Shuling,Bi Xiaoyue,Lin Yanjie,Yang Liu,Li MinghuiORCID,Xie YaoORCID

Abstract

AbstractCefminox sodium is an antimicrobial agent with broad-spectrum antibacterial activity against Gram-positive and Gram-negative bacteria. Cefminox sodium has high security in clinical practice for its few adverse effects such as coagulation dysfunction, which is rare in clinical treatment. Even in patients suffering from chronic liver disease with coagulation dysfunction, it rarely leads to further deterioration of coagulation function. Therefore, patients with chronic liver disease develop severe coagulation dysfunction during the application of cefminox sodium, which is often mistaken for worsening of liver disease other than considered to be the side effect of the drug. Therefore, we report a 55-year-old female patient with liver cirrhosis and hepatocellular carcinoma treated with cefminox sodium intravenously twice for peritonitis. During the treatments, severe coagulopathy occurred, and the coagulation function quickly recovered after drug withdrawal. The diagnosis and treatment of this patient provides us with ideas for dealing with similar problems in clinical practice in the future.

Funder

Beijing Hospitals Authority Clinical medicine Development of special funding support

The Digestive Medical Coordinated Development Center of Beijing Hospitals Authority

National Science and Technology Major Project of China

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Infectious Diseases,Oncology,Epidemiology

Reference17 articles.

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