UPLC-QTOF-MS with chemical profiling approach for rapidly evaluating chemical consistency between traditional and dispensing granule decoctions of Tao-Hong-Si-Wu decoction-Reference-Cited by-同舟云学术

UPLC-QTOF-MS with chemical profiling approach for rapidly evaluating chemical consistency between traditional and dispensing granule decoctions of Tao-Hong-Si-Wu decoction

Published:2012-11-24 Issue:1 Volume:6 Page:
ISSN:1752-153X
Container-title:Chemistry Central Journal
language:en
Short-container-title:Chemistry Central Journal

Author:

Shang Erxin,Zhu Zhenhua,Liu Li,Tang Yuping,Duan Jin-ao

Abstract

AbstractBackgroundIn the present study, chemical consistency between traditional and dispensing granule decoctions of Tao-Hong-Si-Wu decoction was rapidly evaluated by UPLC-QTOF-MS coupled with the MarkerLynx software. Two different kinds of decoctions, namely traditional decoction: water extract of mixed six constituent herbs of Tao-Hong-Si-Wu decoction, and dispensing granules decoction: mixed water extract of each individual herbs of Tao-Hong-Si-Wu decoction, were prepared.ResultsChemical difference was found between traditional and dispensing granule decoctions, and albiflorin, paeoniflorin, gallic acid, amygdalin, and hydroxysafflor yellow A were identified as the significantly changed components during decocting Tao-Hong-Si-Wu decoction. All the peaks of mass spectrum from Tao-Hong-Si-Wu decoction and each herb were extracted and integration by using QuanLynx™. And the optimized data was used for linear regression analysis. The contribution of each herb in Tao-Hong-Si-Wu decoction, and the optimal compatibility proportion of dispensing granule decoction were derived from the linear regression equation.ConclusionsThe optimal dosage proportionality of Tao-Hong-Si-Wu dispensing granule decoction was obtained as 2.5:0.2:1:0.5:0.6:0.1 (DG : CX : BS : SD : TR : HH), which guided better clinic application of Tao-Hong-Si-Wu decoction as dispensing granule decoctions usage, and it also provided some experimental data to reveal the compatibility rule of the relative TCM formulae.

Publisher

Springer Science and Business Media LLC

Subject

General Chemistry

Link

http://link.springer.com/content/pdf/10.1186/1752-153X-6-143.pdf

Reference26 articles.

1. Lin Y, Zhou LL, Wu SS: An idea of traditional decoction reform. Chin J Exp Med Form. 2010, 17: 264-266.

2. Zhang ZW, Sun XM, Zhang XL, Zhang QX: Study on reform of processed Chinese meteria medica. World Sci Tech/Mod Trad Chin Med Mat Med. 2002, 4: 34-38.

3. Xu CB, Li ZJ, Zhu XL, Gu XJ: Progress in the international organization standard for Chinese herbal granules. World Sci Tech/Mod Trad Chin Med Mat Med. 2010, 12: 841-844.

4. Cao PX, Liang GY, Cu VX, Jin FY, He ZY: Determination of glycyrrhizic acid in Ma-Huang Tang decoction by HPLC when decocted separately or as a whole. Chin Trad Herbal Drugs. 2001, 32: 981-982.

5. Lei P, Liu S, Li XZ, Xiao J: Comparison of baicalin between traditional decoction and dispensing granule decoction of Ge-Gen-Qin-Lian formula. Chin Hosp Pharm J. 2005, 25: 1008-1010.

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